Invited Review
نویسندگان
چکیده
Opioids, the wonderful analgesics, remain the mainstay in the clinical management of moderate to severe pain. However, development of analgesic tolerance and increase in pain sensitivity are some of the major concerns following opioid treatment. Studies suggest that NMDA receptor-mediated intracellular events play a role in mediating these effects. Moreover, NMDA receptor antagonists effectively prevent and gradually reverse opioid analgesic tolerance. Collectively, these studies unfold the involvement of NMDA receptor in opioid tolerance.
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On behalf of the editors of mBio, I gratefully acknowledge the following individuals, who served as Invited Editors for the journal in 2014. While not members of the Board of Editors, Invited Editors serve an important role in the review process. Invited Editors are experts in their fields of research who add an additional level of quality to the review process. An Editor may assign a paper to ...
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